ea0032p623 | Growth hormome IGF axis – basic | ECE2013
Deledda Cristiana
, Luciani Paola
, Benvenuti Susanna
, Modi Giulia
, Bossio Alessandro
, Giuliani Corinna
, Fibbi Benedetta
, Peri Alessandro
Introduction: There is evidence that chronic mild hyponatremia (serum (Na+) 130135 mmol/l) may have clinical consequences, such as fracture occurrence and neurological symptoms including unsteadiness, falls and attention deficits. These have been traditionally associated to water movement into nervous cells, as a result of the hypotonic state. The aim of the present study was to determine whether low extracellular sodium directly exerts negative effects on human neuronal...